Riley Arp, Wesley McClain, Andres Gonzales and Jason Gore all earned spots in the 2017 Shell Houston Open through the Monday qualifier.
Arp was the medalist in the 18-hole event on the Tradition Course at Cypresswood Golf Club, shooting 10-under 62 in Spring, Texas.
McClain and Gonzales shot 9-under 63 to avoid a 6-for-1 playoff for the last of the four spots. Jason Gore, a former PGA Tour winner, managed to survive the playoff for the last spot with a birdie on the first playoff hole.
Roger Sloan, Brady Schnell, Martin Trainer, Daniel Chopra and Sebastian Vazquez all were left in the cold after shooting an impressive 64.
Arp played on the Adams Tour mostly last year, though he did miss the cut in the Utah Championship in his lone Web.com Tour start in 2016.
The 26-year-old McClain made four cuts, with two top-10 finishes, in 11 PGA Tour Latinoamerica starts last season.
Gonzales is already on the PGA Tour, making seven cuts in 11 starts this season, including a T-32 last week in Puerto Rico.
Gore is making his fourth start of the season on the PGA Tour, missing the cut in the prior three.